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1

Sex and CYP3A5 genotype influence total CYP3A activity: high CYP3A activity and a unique distribution of CYP3A5 variant alleles in Ethiopians

Gebeyehu, E, Engidawork, E, Bijnsdorp, A, Aminy, A, Diczfalusy, U, Aklillu, E

Journal:

The Pharmacogenomics Journal

Year:

2011

Language:

english

File:

PDF, 379 KB

english, 2011

2

Urinary exosomal proteins as (pan‐)cancer biomarkers: insights from the proteome

Erozenci, L. Ayse, Böttger, Franziska, Bijnsdorp, Irene V., Jimenez, Connie R.

Journal:

Year:

2019

Language:

english

File:

PDF, 1.07 MB

english, 2019

3

Identification of Burkholderia thailandensis with novel genotypes in the soil of central Sierra Leone

Birnie, Emma, van ’t Hof, Senne, Bijnsdorp, Anne, Mansaray, Yembeh, Huizenga, Erdi, van der Ende, Arie, Hugenholtz, Floor, Grobusch, Martin P., Wiersinga, W. Joost, Torres, Alfredo G

Journal:

PLoS Neglected Tropical Diseases

Year:

2019

Language:

english

File:

PDF, 3.88 MB

english, 2019

4

Profiles of family caregivers of patients at the end of life at home: a Q-methodological study into family caregiverâ support needs

Bijnsdorp, Femmy M., Pasman, H. Roeline W., Boot, CÃ©cile R. L., van Hooft, Susanne M., van Staa, AnneLoes, Francke, Anneke L.

Journal:

BMC Palliative Care

Year:

2020

File:

PDF, 481 KB

2020

5

Differential activation of cell death and autophagy results in an increased cytotoxic potential for trifluorothymidine compared to 5-fluorouracil in colon cancer cells

Irene V. Bijnsdorp, Godefridus J. Peters, Olaf H. Temmink, Masakazu Fukushima, Frank A. Kruyt

Journal:

International Journal of Cancer

Year:

2010

Language:

english

File:

PDF, 844 KB

english, 2010

6

Cellular pharmacology of multi- and duplex drugsconsisting of ethynylcytidine and 5-fluoro-2′-deoxyuridine

Irene V. Bijnsdorp, Reto A. Schwendener, Herbert Schott, Iduna Fichtner, Kees Smid, Adrie C. Laan, Sarah Schott, Nienke Losekoot, Richard J. Honeywell, Godefridus J. Peters

Journal:

Investigational New Drugs

Year:

2011

Language:

english

File:

PDF, 204 KB

english, 2011

7

Radiosensitizing potential of the selective cyclooygenase-2 (COX-2) inhibitor meloxicam on human glioma cells

Irene V. Bijnsdorp, Jaap van den Berg, Gitta K. Kuipers, Laurine E. Wedekind, Ben J. Slotman, Johannes van Rijn, M. Vincent M. Lafleur, Peter Sminia

Journal:

Journal of Neuro-Oncology

Year:

2007

Language:

english

File:

PDF, 315 KB

english, 2007

8

Synergistic interaction between trifluorothymidine and docetaxel is sequence dependent

I.V. Bijnsdorp, F.A. Kruyt, S. Gokoel, M. Fukushima, G.J. Peters

Journal:

Year:

2008

Language:

english

File:

PDF, 379 KB

english, 2008

9

Molecular mechanism underlying the synergistic interaction between trifluorothymidine and the epidermal growth factor receptor inhibitor erlotinib in human colorectal cancer cell lines

Irene V. Bijnsdorp, Frank A. E. Kruyt, Masakazu Fukushima, Kees Smid, Shanti Gokoel, Godefridus J. Peters

Journal:

Year:

2010

Language:

english

File:

PDF, 528 KB

english, 2010

10

Thymidine phosphorylase in cancer cells stimulates human endothelial cell migration and invasion by the secretion of angiogenic factors

Bijnsdorp, I V, Capriotti, F, Kruyt, F A E, Losekoot, N, Fukushima, M, Griffioen, A W, Thijssen, V L, Peters, G J

Journal:

British Journal of Cancer

Year:

2011

Language:

english

File:

PDF, 480 KB

english, 2011

11

Lipophilic Prodrugs and Formulations of Conventional (Deoxy)Nucleoside and Fluoropyrimidine Analogs in Cancer

Peters, Godefridus J., Adema, Auke D., Bijnsdorp, Irene V., Sandvold, Marit L.

Journal:

Nucleosides Nucleotides & Nucleic Acids

Year:

2011

Language:

english

File:

PDF, 301 KB

english, 2011

12

Trifluorothymidine Resistance Is Associated with Decreased Thymidine Kinase and Equilibrative Nucleoside Transporter Expression or Increased Secretory Phospholipase A2

Temmink, O. H., Bijnsdorp, I. V., Prins, H. J., Losekoot, N., Adema, A. D., Smid, K., Honeywell, R. J., Ylstra, B., Eijk, P. P., Fukushima, M.

Journal:

Molecular Cancer Therapeutics

Year:

2010

Language:

english

File:

PDF, 430 KB

english, 2010

13

Accumulation of thymidine-derived sugars in thymidine phosphorylase overexpressing cells

I.V. Bijnsdorp, K. Azijli, E.E. Jansen, M.M. Wamelink, C. Jakobs, E.A. Struys, M. Fukushima, F.A.E. Kruyt, G.J. Peters

Journal:

Biochemical Pharmacology

Year:

2010

Language:

english

File:

PDF, 369 KB

english, 2010

14

Trifluorothymidine Induces Cell Death Independently of p53

Bijnsdorp, I. V., Kruyt, F. A., Fukushima, M., Peters, G. J.

Journal:

Nucleosides Nucleotides & Nucleic Acids

Year:

2008

Language:

english

File:

PDF, 213 KB

english, 2008

15

TAS-102: more than an antimetabolite

Godefridus J Peters, Irene V Bijnsdorp

Journal:

The Lancet Oncology

Year:

2012

Language:

english

File:

PDF, 39 KB

english, 2012

16

7 Serumtestosteron speelt een substantiële rol in de groei en progressie van castratieresistent prostaatcarcinoom

T.M. van der Sluis, I.V. Bijnsdorp, E.J.H. Meuleman…

Journal:

Tijdschrift voor Urologie

Year:

2011

Language:

dutch

File:

PDF, 55 KB

dutch, 2011

17

Eiwitten in urine-exosomen identificeren patiënten met gemetastaseerd prostaatkanker

I.V. Bijnsdorp, A.A. Geldof, M. Lavalei, S. Piersma…

Journal:

Tijdschrift voor Urologie

Year:

2012

Language:

dutch

File:

PDF, 303 KB

dutch, 2012

18

Serum testosterone plays an important role in the metastatic ability of castration resistant prostate cancer

Tim M. van der Sluis, Irene V. Bijnsdorp, John J. L. Jacobs…

Journal:

World Journal of Urology

Year:

2013

Language:

english

File:

PDF, 255 KB

english, 2013

19

Deoxyribose Protects Against Rapamycin-Induced Cytotoxicity in Colorectal Cancer Cells In Vitro

Bijnsdorp, I. V., Peters, G. J.

Journal:

Nucleosides Nucleotides & Nucleic Acids

Year:

2011

Language:

english

File:

PDF, 163 KB

english, 2011

20

The Role of Platelet-Derived Endothelial Cell Growth Factor/Thymidine Phosphorylase in Tumor Behavior

Bijnsdorp, I. V., de Bruin, M., Laan, A. C., Fukushima, M., Peters, G. J.

Journal:

Nucleosides Nucleotides & Nucleic Acids

Year:

2008

Language:

english

File:

PDF, 336 KB

english, 2008

21

Increased Migration by Stimulation of Thymidine Phosphorylase in Endothelial Cells of Different Origin

Bijnsdorp, I. V., Vrijland, K., Vroling, L., Fukushima, M., Peters, G. J.

Journal:

Nucleosides Nucleotides & Nucleic Acids

Year:

2010

Language:

english

File:

PDF, 186 KB

english, 2010

22

349 MicroRNAs in urine microvesicles for non-invasive detection of prostate cancer

Bijnsdorp, I.V., Geldof, A.A., Rozendaal, L., Krijsing, O., Koppers-Lalic, D., Würdinger, T., Pegtel, M., Van Moorselaar, R.J.A.

Journal:

European Urology Supplements

Year:

2014

Language:

english

File:

PDF, 108 KB

english, 2014

23

The novel thymidylate synthase inhibitor trifluorothymidine (TFT) and TRAIL synergistically eradicate non-small cell lung cancer cells

Azijli, Kaamar, van Roosmalen, Ingrid A. M., Smit, Jorn, Pillai, Saravanan, Fukushima, Masakazu, de Jong, Steven, Peters, Godefridus J., Bijnsdorp, Irene V., Kruyt, Frank A. E.

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2014

Language:

english

File:

PDF, 1.32 MB

english, 2014

24

Radiosensitization by Thymidine Phosphorylase Inhibitor in Thymidine Phosphorylase Negative and Overexpressing Bladder Cancer Cell Lines

El-Naggar, Maha, Ebbing, Eva, Bijnsdorp, Irene, van den Berg, Jaap, Peters, Godefridus J.

Journal:

Nucleosides Nucleotides & Nucleic Acids

Year:

2014

Language:

english

File:

PDF, 372 KB

english, 2014

25

A predictive role for noncancerous prostate cells: low connexin-26 expression in radical prostatectomy tissues predicts metastasis

Bijnsdorp, I V, Rozendaal, L, van Moorselaar, R J A, Geldof, A A

Journal:

British Journal of Cancer

Year:

2012

Language:

english

File:

PDF, 1.14 MB

english, 2012

26

[18F]Fluoromethylcholine as a Chemotherapy Response Read-Out in Prostate Cancer Cells

Oprea-Lager, Daniela E., van Kanten, Mitchell P., van Moorselaar, Reindert J. A., van den Eertwegh, Alfons J. M., van de Ven, Peter M., Bijnsdorp, Irene V., Hoekstra, Otto S., Geldof, Albert A.

Journal:

Molecular Imaging and Biology

Year:

2015

Language:

english

File:

PDF, 1.16 MB

english, 2015

27

Nontemplated Nucleotide Additions Distinguish the Small RNA Composition in Cells from Exosomes

Koppers-Lalic, Danijela, Hackenberg, Michael, Bijnsdorp, Irene V., van Eijndhoven, Monique A.J., Sadek, Payman, Sie, Daud, Zini, Nicoletta, Middeldorp, Jaap M., Ylstra, Bauke, de Menezes, Renee X., Wü

Journal:

Year:

2014

Language:

english

File:

PDF, 2.35 MB

english, 2014

28

In vitro activity and mechanism of action of a duplex and multidrug of ethynylcytidine and 5-fluorodeoxyuridine

Bijnsdorp, I., Schwendener, R., Schott, H, Schott, S, Fichtner, I, Honeywell, R., Losekoot, N, Laan, A., Peters, G.

Journal:

Nucleic Acids Symposium Series

Year:

2008

File:

PDF, 83 KB

2008

29

Novel cell death mechanisms of trifluorothymidine

Bijnsdorp, I., Kruyt, F, Fukushima, M, Peters, G.

Journal:

Nucleic Acids Symposium Series

Year:

2008

File:

PDF, 99 KB

2008

30

In Vivo and in Vitro Activity And Mechanism Of Action of the Multidrug Cytarabine-L-Glycerylyl-Fluorodeoxyuridine

Bijnsdorp, Irene V., Schwendener, Reto A., Schott, Herbert, Fichtner, Iduna, Smid, Kees, Schott, Sarah, Laan, Adrie C., Peters, Godefridus J.

Journal:

Nucleosides Nucleotides & Nucleic Acids

Year:

2007

Language:

english

File:

PDF, 111 KB

english, 2007

31

Thymidine phoshorylase as a target for antiangiogenesis treatment

Peters, G., Bijnsdorp, I., Fukushima, M

Journal:

Nucleic Acids Symposium Series

Year:

2008

File:

PDF, 88 KB

2008

32

Innovations and Opportunities to Improve Conventional (Deoxy)Nucleoside and Fluoropyrimidine Analogs in Cancer

Adema, A., Bijnsdorp, I., Sandvold, M., Verheul, H., Peters, G.

Journal:

Current Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 423 KB

english, 2009

33

Mechanisms of action of FdUMP[10]: Metabolite activation and thymidylate synthase inhibition

Bijnsdorp, I., Comijn, E., Padron, J., Gmeiner, W., Peters, G.

Journal:

Oncology Reports

Year:

2007

Language:

english

File:

PDF, 77 KB

english, 2007

34

Exosomal ITGA3 interferes with non-cancerous prostate cell functions and is increased in urine exosomes of metastatic prostate cancer patients

Bijnsdorp, Irene V., Geldof, Albert A., Lavaei, Mehrdad, Piersma, Sander R., van Moorselaar, R. Jeroen A., Jimenez, Connie R.

Journal:

Journal of Extracellular Vesicles

Year:

2013

Language:

english

File:

PDF, 1.30 MB

english, 2013

35

Feasibility of urinary extracellular vesicle proteome profiling using a robust and simple, clinically applicable isolation method

Bijnsdorp, Irene V., Maxouri, Olga, Kardar, Aarzo, Schelfhorst, Tim, Piersma, Sander R., Pham, Thang V., Vis, Andre, van Moorselaar, R. Jeroen, Jimenez, Connie R.

Journal:

Journal of Extracellular Vesicles

Year:

2017

Language:

english

File:

PDF, 1.95 MB

english, 2017

36

The Non-Coding Transcriptome of Prostate Cancer: Implications for Clinical Practice

Bijnsdorp, Irene V., van Royen, Martin E., Verhaegh, Gerald W., Martens-Uzunova, Elena S.

Journal:

Molecular Diagnosis & Therapy

Year:

2017

Language:

english

File:

PDF, 968 KB

english, 2017

37

Protein Complexes in Urine Interfere with Extracellular Vesicle Biomarker Studies

Wachalska, Magda, Koppers-Lalic, Danijela, van Eijndhoven, Monique, Pegtel, Michiel, Geldof, Albert A., Lipinska, Andrea D., van Moorselaar, R. Jeroen, Bijnsdorp, Irene V.

Journal:

Journal of Circulating Biomarkers

Year:

2016

Language:

english

File:

PDF, 701 KB

english, 2016

38

Plasma FGF23 is not elevated in prostate cancer

Vlot, Mariska C., Bijnsdorp, Irene, den Heijer, Martin, de Jonge, Robert, van Moorselaar, R. Jeroen A., Heijboer, Annemieke C.

Journal:

Clinica Chimica Acta

Year:

2017

Language:

english

File:

PDF, 861 KB

english, 2017

39

Large-Scale Urinary Proteome Dataset Across Tumor Types Reveals Candidate Biomarkers for Lung Cancer

Bijnsdorp, Irene V., Jimenez, Connie R.

Journal:

Year:

2018

Language:

english

File:

PDF, 168 KB

english, 2018

40

A protocol for urine collection and storage prior to DNA methylation analysis

Bosschieter, J., Bach, S., Bijnsdorp, I. V., Segerink, L. I., Rurup, W. F., van Splunter, A. P., Bahce, I., Novianti, P. W., Kazemier, G., van Moorselaar, R. J. A., Steenbergen, R. D. M., Nieuwenhuijz

Journal:

Year:

2018

Language:

english

File:

PDF, 2.15 MB

english, 2018

41

Changes in the urinary extracellular vesicle proteome are associated with nephronophthisis-related ciliopathies

Stokman, Marijn F., Bijnsdorp, Irene V., Schelfhorst, Tim, Pham, Thang V., Piersma, Sander R., Knol, Jaco C., Giles, Rachel H., Bongers, Ernie M.H.F., Knoers, Nine V.A.M., Lilien, Marc R., Jiménez, Co

Journal:

Journal of Proteomics

Year:

2018

Language:

english

File:

PDF, 2.13 MB

english, 2018

42

TYMP (thymidine phosphorylase)

Bijnsdorp, IV, Peters, GJ

Journal:

Atlas of Genetics and Cytogenetics in Oncology and Haematology

Year:

2011

Language:

english

File:

PDF, 313 KB

english, 2011

43

Identification of Burkholderia thailandensis with novel genotypes in the soil of central Sierra Leone

Birnie, Emma, van ’t Hof, Senne, Bijnsdorp, Anne, Mansaray, Yembeh, Huizenga, Erdi, van der Ende, Arie, Hugenholtz, Floor, Grobusch, Martin P., Wiersinga, W. Joost, Torres, Alfredo G

Journal:

PLoS Neglected Tropical Diseases

Year:

2019

File:

PDF, 3.88 MB

2019

44

Prostate Cancer Development Is Not Affected by Statin Use in Patients with Elevated PSA Levels

Meijer, Dennie, van Moorselaar, R. Jeroen A., Vis, André N., Bijnsdorp, Irene V.

Journal:

Year:

2019

Language:

english

File:

PDF, 835 KB

english, 2019

45

Prostate Cancer Development Is Not Affected by Statin Use in Patients with Elevated PSA Levels

Meijer, Dennie, van Moorselaar, R. Jeroen A., Vis, André N., Bijnsdorp, Irene V.

Journal:

Year:

2019

File:

PDF, 835 KB

2019

46

Zorgnetwerken

Bijnsdorp, Femmy M., van Groenou, Marjolein I. Broese, Francke, Anneke L., Pasman, H. Roeline W., Evans, Natalie, Peeters, Carel F. W., Kruijswijk, Wilco

Journal:

Year:

2018

File:

PDF, 4.53 MB

2018

47

Home care for terminally ill patients: the experiences of family caregivers with and without paid work

Bijnsdorp, Femmy M, van der Beek, Allard J, Pasman, H Roeline W, Boot, CÃ©cile R L, de Boer, Alice H, Plaisier, Inger, Onwuteaka-Philipsen, Bregje D

Journal:

BMJ Supportive & Palliative Care

Year:

2019

File:

PDF, 305 KB

2019

48

DPHL: A DIA Pan-human Protein Mass Spectrometry Library for Robust Biomarker Discovery

Zhu, Tiansheng, Zhu, Yi, Xuan, Yue, Gao, Huanhuan, Cai, Xue, Piersma, Sander R., Pham, Thang V., Schelfhorst, Tim, Haas, Richard R.G.D., Bijnsdorp, Irene V., Sun, Rui, Yue, Liang, Ruan, Guan, Zhang, Q

Journal:

Genomics, Proteomics & Bioinformatics

Year:

2020

File:

PDF, 1.06 MB

2020

49

Identification of the prostate cancer exosome surface proteome and its application to detect prostate cancer in urine

Erozenci, A., Feenstra, F., Jenster, G., Van Moorselaar, R.J., Piersma, S., Jimenez, C., Bijnsdorp, I.

Journal:

European Urology Open Science

Year:

2020

File:

PDF, 87 KB

2020

50

Het combineren van meerdere rollen onder ouderen: vermindert of verbetert dit het welbevinden?

Bijnsdorp, F.M., Suanet, B., Broese van Groenou, M.I.

Journal:

Mens en maatschappij

Year:

2018

File:

PDF, 372 KB

2018

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